Silvestre y la Piedrecita Magica
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Silvestre y la Piedrecita Magica by William Steig
The most meaningful reward to clinicians and researchers is the absence of recurrent malignancy in their patients. While in some patients the disease will be cured by resection alone, in other similarly staged cases the disease will recur despite adequate loco regional and systemic therapies. Hence, risk assessment is a complex issue with many related or unrelated prognostic factors determining outcome. The purpose of this volume is to review some of the most relevant prognostic factors of newly diagnosed breast cancer, focusing on fea- tures determining the magnitude of risk. The ultimate value of establishing the significance of each prognostic factor in a given patient will be the resulting ability to plan individu- alized therapies for patients at different risk of recurrence at the time of diagnosis. To secure the maximum benefit for high-risk patients, while avoiding undue toxicity in those with low-risk lesions, a well-integrated analysis of all known prognostic factors will be essential in the early postdiagnos- tic period. In addition to well-established staging criteria such as axillary nodes, tumor size, receptors, scanning and radiographic examinations, the more sophisticated labora- tory techniques, as discussed by several authors herein, will playa crucial role in risk assessment. Most of them, - ploidy determination, oncogenes, tumor markers, monoclonal anti- bodies, growth factors, etc. -are presently available in only a minority of treatment centers.
William Steig (1907-2003) was a cartoonist, illustrator, and author of award-winning books for children, including Shrek!, on which the DreamWorks movies are based. Steig was born in New York City. Every member of his family was involved in the arts, and so it was no surprise when he decided to become an artist. He attended City College and the National Academy of Design. In 1930, Steig's work began appearing in The New Yorker, where his drawings have been a popular fixture ever since. He published his first children's book, Roland the Minstrel Pig, in 1968. In 1970, Steig received the Caldecott Medal for Sylvester and the Magic Pebble. His books for children also include Dominic; The Real Thief; The Amazing Bone, a Caldecott Honor Book; Amos & Boris, a National Book Award finalist; and Abel's Island and Doctor De Soto, both Newbery Honor Books. Steig's books have also received the Christopher Award, the Irma Simonton Black Award, the William Allen White Children's Book Award, and the American Book Award. His European awards include the Premio di Letteratura per l'infanzia (Italy), the Silver Pencil Award (the Netherlands), and the Prix de la Fondation de France. On the basis of his entire body of work, Steig was selected as the 1982 U.S. candidate for the Hans Christian Andersen Medal for Illustration and subsequently as the 1988 U.S. candidate for Writing. Steig also published thirteen collections of drawings for adults, beginning with About People in 1939, and including The Lonely Ones, Male/Female, The Agony in the Kindergarten, and Our Miserable Life. He died in Boston at the age of 95.
Quentin Blake is Childrens Laureate of Great Britain, has won the Kate Greenaway Medal, and is the author and/or illustrator of many books. He lives in London, England.
SKU | CIN0962516279VG |
ISBN 13 | 9780962516276 |
ISBN 10 | 0962516279 |
Title | Silvestre y la Piedrecita Magica |
Author | William Steig |
Condition | Very Good |
Binding Type | Paperback |
Publisher | Lectorum Publications |
Year published | 1996-03-01 |
Number of pages | 0 |
Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
Note | This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us |